Prophecy 2 / 2026-10-25

What does a DNR order actually change?

A new DNR-only order is followed by changes in ventilation and monitoring, but these associations are weaker under stricter overlap restrictions, while a profound short-term mortality gap remains. We cannot attribute deaths or treatment withdrawal to the DNR order itself.

Published results

Research status: Exploratory · DNR effect not identified

A new DNR-only order is followed by changes in ventilation and monitoring, but these associations are weaker under stricter overlap restrictions, while a profound short-term mortality gap remains. We cannot attribute deaths or treatment withdrawal to the DNR order itself.

DNR event histories

Eligible DNR orders3,021
Measured common support2,014

Clinical exposures

DNR only: 792 events; 12h hospital mortality 19.32% versus 1.70% in selected comparators. Association only, not a causal effect.

DNR + DNI: 1,222 events; 12h hospital mortality 15.38% versus 1.41% in selected comparators. Association only, not a causal effect.